Enantiomeric Discrimination by Surface‐Enhanced Raman Scattering–Chiral Anisotropy of Chiral Nanostructured Gold Films

作者：Zexi Liu, Jing Ai, Prashant Kumar, En‐Ming You, Xiong Zhou, Xi Liu, Zhong‐Qun Tian, Petr Bouř, Yingying Duan, Lu Han, Nicholas A. Kotov, Song‐Yuan Ding, Shunai Che · 发表于：Angewandte Chemie International Edition · 年份：2020 · DOI：10.1002/anie.202006486 · 被引用次数：153 · 研究领域：Gold and Silver Nanoparticles Synthesis and Applications、Nanocluster Synthesis and Applications、Molecular spectroscopy and chirality

A surface-enhanced Raman scattering-chiral anisotropy (SERS-ChA) effect is reported that combines chiral discrimination and surface Raman scattering enhancement on chiral nanostructured Au films (CNAFs) equipped in the normal Raman scattering Spectrometer. The CNAFs provided remarkably higher enhancement factors of Raman scattering (EFs) for particular enantiomers, and the SERS intensity was proportional to the enantiomeric excesses (ee) values. Except for molecules with mesomeric species, all of the tested enantiomers exhibited high SERS-ChA asymmetry factors (g), ranging between 1.34 and 1.99 regardless of polarities, sizes, chromophores, concentrations and ee. The effect might be attributed to selective resonance coupling between the induced electric and magnetic dipoles associated with enantiomers and chiral plasmonic modes of CNAFs.