[Effect of electroacupuncture at "Zusanli" (ST 36) and "Yanglingquan" (GB 34) on perinatal nicotine-exposure-induced lung function and morphology of neonatal rats].

作者：Hang Su, Bo Ji, Guozhen Zhao, Yitian Liu, Yunpeng Ge, Jian Dai, Yawen Lu, Dan Wang, Reiko Sakurai, Virender K. Rehan, Ming-Na Yan, Xiaomin Sun, Hong-Xin Bai, Meng-Wei Guo, Xiao-Xuan Ren · 发表于：PubMed · 年份：2019 · DOI：10.13703/j.0255-2930.2019.06.017 · 被引用次数：1 · 研究领域：Acupuncture Treatment Research Studies、Neonatal Respiratory Health Research、Andrographolide Research and Applications

OBJECTIVE: induced lung function and morphology of newborn rats and explore the rule of acupoint effect in EA for the prevention from lung dysplasia in newborn rats. METHODS: exposure model. Simultaneously, during model preparation, EA was applied at "Zusanli" (ST 36) and "Yanglingquan" (GB 34) in the N+ST 36 group and the N+GB 34 group respectively, once a day, through to the 21st postnatal day. The lung function analytic system for small animal was adopted to observe the changes in lung function indicators in newborn rats, such as peak inspiratory flow (PIF), peak expiratory flow (PEF), expiratory resistance (RE), inspiratory resistance (RI) and dynamic compliance (Cdyn). HE staining was used to observe the morphological changes of lung, such as alveolar fusion and rupture. RESULTS: >0.05). CONCLUSION: induced lung function and morphology of newborn rats than electroacupuncture at "Yanglingquan" (GB 34).