Distinct features of SARS-CoV-2-specific IgA response in COVID-19 patients

作者：Hai-qiong Yu, Bao-qing Sun, Zhang-fu Fang, Jin-cun Zhao, Xiaoyu Liu, Yimin Li, Xi-zhuo Sun, Hong-feng Liang, Bei Zhong, Zhi-feng Huang, Pei-yan Zheng, Li-feng Tian, Hui‐Qi Qu, De-chen Liu, Er-yi Wang, Xiao-jun Xiao, Shi-yue Li, Feng Ye, Li Guan, Dong-sheng Hu, Håkon Håkonarson, Zhi-Gang Liu, Nanshan Zhong · 发表于：European Respiratory Journal · 年份：2020 · DOI：10.1183/13993003.01526-2020 · 被引用次数：352 · 研究领域：SARS-CoV-2 and COVID-19 Research、COVID-19 Clinical Research Studies、Immune responses and vaccinations

Humoral immune response to SARS-CoV-2 showed an early response of IgA, instead of IgM, in COVID-19 patients. As highlighted by this study, enhanced IgA responses observed in severe COVID-19 might confer damaging effects in severe COVID-19. https://bit.ly/3fA7c1I