Effects of moxibustion on symptoms of mild cognitive impairment: protocol of a systematic review and meta-analysis

作者：Tao Zhang, Linpeng Wang, Guiling Wang, Jing-Qing Sun, Xue-Wen Mao, Huili Jiang, Bin Li, Cun‐Zhi Liu · 发表于：BMJ Open · 年份：2020 · DOI：10.1136/bmjopen-2019-033910 · 被引用次数：9 · 研究领域：Acupuncture Treatment Research Studies、Intensive Care Unit Cognitive Disorders、Nausea and vomiting management

Introduction Mild cognitive impairment (MCI) is considered the intermediate phase between normal age-related cognitive decline and dementia. Moxibustion has gained increased popularity for the management of MCI in China.This study aimed to evaluate the effects and safety of moxibustion on symptoms of MCI. Methods and analysis Four English databases and six Chinese databases will be searched from their inception to October 2019: Embase, MEDLINE, Cochrane Central Register of Controlled Trials, Allied and Complementary Medicine Database, China National Knowledge Infrastructure, Chongqing VIP Chinese Science and Technology Periodical Database, Wanfang Database, SinoMed, China Doctoral Dissertations Full-text Database and the China Master’s Theses Full-text Database. Only clinical randomised controlled trials and the first period in randomised cross-over trial related to moxibustion for MCI will be included. The primary outcomes include the improvement of cognitive function, as measured by validated assessment tools. The secondary outcomes include changes in the activity of daily living scale, effective rate and the incidences of adverse events. The selection of studies, data extraction and risk of bias assessment will be carried out by two independent reviewers. Review Manager V.5.3 software will be used for statistical analyses. Heterogeneity test, data synthesis and subgroup analysis will be performed if necessary. The risk of bias of included studies will be assessed by the Co...