Prevalence and incidence of vector-borne pathogens in unprotected dogs in two Brazilian regions

作者：Filipe Dantas‐Torres, Luciana Aguiar Figueredo, Kamila Gaudêncio da Silva Sales, Débora Elienai de Oliveira Miranda, Joanna Alexandre, Yury Yzabella da Silva, Lidiane Gomes da Silva, Guilherme Ribeiro Valle, Vítor Márcio Ribeiro, Domenico Otranto, Katrin Deuster, Matthias Pollmeier, Gertraut Altreuther · 发表于：Parasites & Vectors · 年份：2020 · DOI：10.1186/s13071-020-04056-8 · 被引用次数：45 · 研究领域：Research on Leishmaniasis Studies、Trypanosoma species research and implications、Virology and Viral Diseases

BACKGROUND: Various vector-borne pathogens (VBPs) affect dogs worldwide, with their diversity and force of infection being usually higher in the tropics. Cross-sectional studies have been conducted to investigate the prevalence of VBPs in dogs, but data from longitudinal studies are scarce. Herein, we assessed the prevalence and the year-crude incidence (YCI) of Leishmania spp. and other VBPs in privately-owned dogs from two geographical regions of Brazil. METHODS: A total of 823 dogs were initially screened for Leishmania spp. by both serology and polymerase chain reaction (PCR). From the negatives, 307 (103 from São Joaquim de Bicas, Minas Gerais, and 204 from Goiana, Pernambuco) were randomly selected for the longitudinal study. These dogs were tested for various VBPs at baseline, after 8 and 12 months. RESULTS: Out of 823 dogs initially screened, 131 (15.9%) were positive for Leishmania spp. Out of the 307 dogs enrolled in the longitudinal study, 120 (39.1%) were lost for different reasons (e.g. animal death, owner decision, and lost to follow-up). In São Joaquim de Bicas, the baseline prevalence and YCI were as follows: 16.5% and 7.1% for Anaplasma spp.; 81.6% and 100% for Babesia spp.; 0% and 1.3% (only one faint positive) for Dirofilaria immitis; 37.9% and 22.9% for Ehrlichia spp.; 19.5% and 43.8% for Leishmania spp. In Goiana, the baseline prevalence and YCI were as follows: 45.1% and 38.3% for Anaplasma spp.; 79.9% and 96.0% for Babesia spp.; 36.3% and 39.8% for D. i...