Tandem CAR T cells targeting HER2 and IL13Rα2 mitigate tumor antigen escape

作者：Meenakshi G. Hegde, Malini Mukherjee, Zakaria Grada, Antonella Pignata, Daniel B. Landi, Shoba A. Navai, Amanda Wakefield, Kristen Fousek, Kevin Bielamowicz, Kevin K. H. Chow, Vita S. Brawley, Tiara T. Byrd, Simone S. Krebs, Stephen M Gottschalk, Winfried S. Wels, Matthew L. Baker, Gianpietro Dotti, Maksim Mamonkin, Malcolm K. Brenner, Jordan Scott Orange, Nabil M. Ahmed · 发表于：Journal of Clinical Investigation · 年份：2019 · DOI：10.1172/jci131246 · 被引用次数：33 · 研究领域：CAR-T cell therapy research、Nanowire Synthesis and Applications、Immunotherapy and Immune Responses

The corresponding author recently notified the JCI that the patient data presented in Figure Analysis of the correct patient data set does not show a significant difference in CERS6 expression in human lung adenocarcinomas with positive invasive growth (definite) compared with those with negligible invasive growth or without invasive growth (focal/none). The Editors have requested an institutional investigation into this matter, and we will inform our readers of the outcome when the investigation is complete.