The Na + -K + -ATPase is needed in glia of touch receptors for responses to touch in C. elegans

作者：Christina K. Johnson, Jesús Fernandez-Abascal, Ying Wang, Lei Wang, Laura Bianchi · 发表于：Journal of Neurophysiology · 年份：2020 · DOI：10.1152/jn.00636.2019 · 被引用次数：21 · 研究领域：Genetics, Aging, and Longevity in Model Organisms、Circadian rhythm and melatonin、Neurobiology and Insect Physiology Research

Increasing evidences support that accessory cells in mechanosensors regulate neuronal output; however, the glial molecular mechanisms that control this regulation are not fully understood. We show here in Caenorhabditis elegans that specific glial Na + -K + -ATPase genes are needed for nose touch-avoidance behavior. Our data support the requirement of these Na + -K+-ATPases for homeostasis of Na + and K + in nose touch receptors. Our data add to our understanding of glial regulation of mechanosensors.