Intraoperative dexmedetomidine-induced polyuria from a loading dose: a case report

作者：Zhang Chen, Ting Chen, Haiwang Ye, Junping Chen, Bo Lu · 发表于：Journal of International Medical Research · 年份：2020 · DOI：10.1177/0300060520910643 · 被引用次数：20 · 研究领域：Anesthesia and Sedative Agents、Intensive Care Unit Cognitive Disorders、Electrolyte and hormonal disorders

With extensive perioperative use of dexmedetomidine, there has been rising concern about its side effects, which are most commonly bradycardia and hypotension. However, increased urine output or diuresis is not well recognized with perioperative use of dexmedetomidine. We report a case of intraoperative polyuria induced by dexmedetomidine. The unusual feature of this case is that only a loading dose of dexmedetomidine was administered, but there was a long-lasting and large effect of diuresis. The findings from our case suggest that clinicians should be alert to the risk of diuresis when using dexmedetomidine.