Combinatorial single-cell CRISPR screens by direct guide RNA capture and targeted sequencing

作者：Joseph M. Replogle, Thomas M. Norman, Albert Xu, Jeffrey A. Hussmann, Jin Chen, J. Zachery Cogan, Elliott J. Meer, Jessica M. Terry, Daniel P. Riordan, Niranjan Srinivas, Ian T. Fiddes, Joseph G. Arthur, Luigi J. Alvarado, Katherine A. Pfeiffer, Tarjei S. Mikkelsen, Jonathan S. Weissman, Britt Adamson · 发表于：Nature Biotechnology · 年份：2020 · DOI：10.1038/s41587-020-0470-y · 被引用次数：511 · 研究领域：CRISPR and Genetic Engineering、Single-cell and spatial transcriptomics、RNA and protein synthesis mechanisms