An Exercise Program for Peritoneal Dialysis Patients in the United States: A Feasibility Study

作者：Paul N. Bennett, Wael F. Hussein, Kimberly Matthews, Mike West, Erick Smith, Marc Reiterman, Grace Alagadan, Bryan Shragge, Jignesh Patel, Brigitte Schiller · 发表于：Kidney Medicine · 年份：2020 · DOI：10.1016/j.xkme.2020.01.005 · 研究领域：Dialysis and Renal Disease Management、Parathyroid Disorders and Treatments、Chronic Kidney Disease and Diabetes

Background People with end-stage kidney disease receiving peritoneal dialysis (PD) are generally physically inactive and frail. Exercise studies in PD are scarce and currently there are no PD exercise programs in the United States. The primary objective of this study was to test the feasibility of a combined resistance and cardiovascular exercise program for PD patients under the care of a dedicated home dialysis center in the United States. Study Design Parallel randomized controlled feasibility study. Setting & Participants PD patients were recruited from a single center and randomly assigned to the intervention (exercise; n = 18) or control (nonexercise; n = 18) group. Intervention The intervention group received monthly exercise physiologist consultation, exercise prescription (resistance and aerobic exercise program using exercise bands), and 4 exercise support telephone calls over 12 weeks. The control group received standard care. Outcomes The primary outcome was study feasibility as measured by eligibility rates, recruitment rates, retention rates, adherence rates, adverse events, and sustained exercise rates. Secondary outcome measures were changes in physical function (sit-to-stand test, timed-up-and-go test, and pinch-strength tests) and patient-reported outcome measures. Results From a single center with 75 PD patients, 57 (76%) were deemed eligible, resulting in a recruitment rate of 36 (63%) patients. Participants were randomly assigned into 2 groups of 18 (1:1)...