2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes

作者：Juhani Knuuti, William Wijns, Antti Saraste, Davide Capodanno, Emanuele Barbato, Christian Funck‐Brentano, Eva Prescott, Robert F. Storey, Christi Deaton, Thomas Cuisset, Stefan Agewall, Kenneth Dickstein, Thor Edvardsen, Javier Escaned, Bernard J. Gersh, Pavel Svítil, Martine Gilard, David Hasdai, Róbert Hatala, Felix Mahfoud, Josep Masip, Claudio Muneretto, Marco Valgimigli, Stephan Achenbach, Jeroen J. Bax, ESC Scientific Document Group, Franz-Josef Neumann, Udo Sechtem, Adrian Banning, Nikolaos Bonaros, Héctor Bueno, Raffaele Bugiardini, Alaide Chieffo, Filippo Crea, Martin Czerny, Victoria Delgado, Paul Dendale, Frank A. Flachskampf, H. Gohlke, Erik Lerkevang Grove, Stefan James, Demosthenes G. Katritsis, Ulf Landmesser, Maddalena Lettino, Christian M. Matter, Hendrik M. Nathoe, Alexander Niessner, Carlo Patrono, Anna Sonia Petronio, S. Pettersen, Raffaele Piccolo, Massimo Piepoli, Bogdan A Popescu, Lorenz Räber, Dimitrios Richter, Marco Roffi, Franz Xaver Roithinger, Е. V. Shlyakhto, Dirk Sibbing, Sigmund Silber, Iain Simpson, Miguel Sousa‐Uva, Panos Vardas, Adam Witkowski, Jose Luis Zamorano, Stephan Achenbach, Stefan Agewall, Emanuele Barbato, Jeroen J. Bax, Davide Capodanno, Thomas Cuisset, Christi Deaton, Kenneth Dickstein, Thor Edvardsen, Javier Escaned, Christian Funck‐Brentano, Bernard J Gersh, Martine Gilard, David Hasdai, Róbert Hatala, Felix Mahfoud, Josep Masip, Claudio Muneretto, Eva Prescott, Antti Saraste, Robert F. Storey, Pavel Svitil, Marco Valgimigli, Stephan Windecker, Victor Aboyans, Colin Baigent, Jean-Philippe Collet, Veronica Dean, Victoria Delgado, Donna Fitzsimons, Chris P Gale, Diederick E. Grobbee, Sigrun Halvorsen, Gerhard Hindricks, Bernard Iung, Peter Jüni, Hugo A. Katus, Ulf Landmesser, Christophe Leclercq, Maddalena Lettino, Basil S. Lewis, Béla Merkely, Christian Mueller, Steffen E. Petersen, Anna Sonia Petronio, Dimitrios Richter, Marco Roffi, Е. V. Shlyakhto, Iain Simpson, Miguel Sousa‐Uva, Rhian M. Touyz, Salim Benkhedda, Bernhard Metzler, V Sujayeva, Bernard Cosyns, Zumreta Kušljugić, Vasil Velchev, Georgios Panayi, Petr Kala, Sune Ammentorp Haahr-Pedersen, Hamza Kabil, Tiia Ainla, Tomi Kaukonen, Guillaume Cayla, Zurab Pagava, Jochen Wöehrle, John Kanakakis, Kálmán Tóth, Þórarinn Guðnason, Aaron Peace, Doron Aronson, Carmine Riccio, Shpend Elezi, Erkin М Мirrakhimov, Silvija Hansone, Antoine Sarkis, Rūta Marija Babarskienė, Jean Beissel, Andrew J Cassar Maempel, Valeriu Revenco, Greetje J. de Grooth, Hristo Pejkov, Vibeke Juliebø, Piotr Lipiec, José Santos, Ovidiu Chioncel, D. V. Duplyakov, Luca Bertelli, Ana Djordjević Dikić, Martin Studenčan, Matjaž Bunc, Fernándo Alfonso, Magnus Bäck, Michael J. Zellweger, Faouzi Addad, Aylin Yı́ldı́rı́r, Yu.M. Sіrenko, Brian Clapp · 发表于：European Heart Journal · 年份：2019 · DOI：10.1093/eurheartj/ehz425 · 被引用次数：7226 · 研究领域：Cardiac Imaging and Diagnostics、Acute Myocardial Infarction Research、Cardiac, Anesthesia and Surgical Outcomes

Coronary artery disease (CAD) is a pathological process characterized by atherosclerotic plaque accumulation in the epicardial arteries, whether obstructive or non-obstructive. This process can be modified by lifestyle adjustments, pharmacological therapies, and invasive interventions designed to achieve disease stabilization or regression. The disease can have long, stable periods but can also become unstable at any time, typically due to an acute atherothrombotic event caused by plaque rupture or erosion. However, the disease is chronic, most often progressive, and hence serious, even in clinically apparently silent periods. The dynamic nature of the CAD process results in various clinical presentations, which can be conveniently categorized as either acute coronary syndromes (ACS) or chronic coronary syndromes (CCS). The Guidelines presented here refer to the management of patients with CCS. The natural history of CCS is illustrated in Figure 1.