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Impact of Kissing Balloon in Patients Treated With Ultrathin Stents for Left Main Lesions and Bifurcations

作者:Luca Gaido, Fabrizio D’Ascenzo, Yoichi Imori, Wojciech Wojakowski, Andrea Saglietto, Filippo Figini, Alessio Mattesini, Daniela Trabattoni, Andrea Rognoni, Francesco Tomassini, Alessandro Bernardi, Nicola J. Ryan, Saverio Muscoli, Gérard Helft, Ovidio DE FILIPPO, Radosław Parma, Leonardo De Luca, Fabrizio Ugo, Enrico Cerrato, Antonio Montefusco, Mauro Pennacchi, Wojciech Wańha, Grzegorz A. Smolka, Giulia DE LIO, Francesco Bruno, Zenon Huczek, Giacomo Giovanni Boccuzzi, Bernardo Cortese, Davide Capodanno, Pierluigi Omedè, Massimo Mancone, Ivan Javier Nuñez-Gil, Francesco Romeo, Ferdiando Varbella, Mauro Rinaldi, Javier Escaned, Federico Conrotto, Francesco Burzotta, Alaide Chieffo, Leor Perl, Maurizio D’Amico, Carlo Di Mario, Imad Sheiban, Andrea Gagnor, Massimo Giammaria, Gaetano Maria De Ferrari · 发表于:Circulation Cardiovascular Interventions · 年份:2020 · DOI:10.1161/circinterventions.119.008325 · 被引用次数:60 · 研究领域:Coronary Interventions and Diagnostics、Cardiac Imaging and Diagnostics、Acute Myocardial Infarction Research

Background: There are limited data regarding the impact of final kissing balloon (FKI) in patients treated with percutaneous coronary intervention using ultrathin stents in left main or bifurcations. Methods: All patients undergoing left main or bifurcations percutaneous coronary intervention enrolled in the RAIN registry (Very Thin Stents for Patients With MAIN or BiF in Real Life: The RAIN, a Multicenter Study) evaluating ultrathin stents were included. Major adverse cardiac event (a composite of all-cause death, myocardial infarction, target lesion revascularization, and stent thrombosis) was the primary end point, while its components, along with target vessel revascularization, were the secondary end points. The main analysis was performed comparing patients with and without FKI after adjustment with inverse probability of treatment weighting. Subgroup analyses were performed according to FKI (short [<3 mm] versus long overlap), strategy (provisional versus 2-stent), routine versus bail-out FKI, and the use of imaging and proximal optimization technique. Results: Two thousand seven hundred forty-two patients were included. At 16 months (8–20) follow-up, inverse probability of treatment weighting adjusted rates of major adverse cardiac event were similar between FKI and no-FKI group (15.1% versus 15.5%; P =0.967), this result did not change with use of imaging, proximal optimization technique, or routine versus bail-out FKI. In the 2-stent subgroup, FKI was associated wit...