Copper-Catalyzed Disulfonation of Terminal Alkynes with Sodium Arylsulfinates

作者：Zhenhua Liu, Lin Yang, Kaining Zhang, Wanjiao Chen, Yu Tian, Lianxiao Wang, Wen Gao, Bo Tang · 发表于：Organic Letters · 年份：2020 · DOI：10.1021/acs.orglett.0c00575 · 被引用次数：29 · 研究领域：Sulfur-Based Synthesis Techniques、Chemical Synthesis and Reactions、Catalytic C–H Functionalization Methods

A novel and direct disulfonylation reaction of commercially available terminal alkynes under copper(I)/bromodifluoroacetate cocatalyst has been realized. This protocol provides a facile and practical pathway to selectively access (E)-1,2-disulfonylethenes, in which features good functional group compatibility, easily available starting materials, and excellent stereoselectivity with good yields.