Blood-stage malaria parasites manipulate host innate immune responses through the induction of sFGL2

作者：Yong Fu, Yan Ding, Qinghui Wang, Feng Zhu, Yulong Tan, Lu Xiao, Bo Guo, Qingfeng Zhang, Yaming Cao, Taiping Liu, Liwang Cui, Wenyue Xu · 发表于：Science Advances · 年份：2020 · DOI：10.1126/sciadv.aay9269 · 被引用次数：32 · 研究领域：Complement system in diseases、Malaria Research and Control、Mosquito-borne diseases and control

from inducing macrophages to release MCP-1. Therefore, we highlight a previously unrecognized immune suppression strategy of malaria parasites and uncover the fundamental mechanism of sFGL2 to suppress host innate immune responses.