Supramolecular Hyaluronic Assembly with Aggregation-Induced Emission Mediated in Two Stages for Targeting Cell Imaging

作者：Yang Yang, Ya‐Jun Jin, Xin Jia, Shi-Kuo Lu, Zerui Fu, Yu-xi Liu, Yu Liu, Yu Liu, Yu Liu · 发表于：ACS Medicinal Chemistry Letters · 年份：2020 · DOI：10.1021/acsmedchemlett.9b00559 · 被引用次数：12 · 研究领域：Luminescence and Fluorescent Materials、Molecular Sensors and Ion Detection、Polydiacetylene-based materials and applications

Supramolecular aggregation-induced emission (AIE) has become a research hotspot in cell imaging. Herein, supramolecular assembly with AIE effect was constructed in two stages, where adamantane modified tetraphenylethene self-assembly emitted weak fluorescence, and then after adding β-cyclodextrin modified hyaluronic acid, the formed nanoparticles enhanced AIE fluorescence for targeted cancer cell imaging.