Cartilage repair mediated by thermosensitive photocrosslinkable TGFβ1-loaded GM-HPCH via immunomodulating macrophages, recruiting MSCs and promoting chondrogenesis

作者：Xiongfa Ji, Zehua Lei, Meng Yuan, Hao Zhu, Xi Yuan, Wenbin Liu, Hongxu Pu, Jiawei Jiang, Yu Zhang, Xulin Jiang, Jun Xiao · 发表于：Theranostics · 年份：2020 · DOI：10.7150/thno.41622 · 被引用次数：77 · 研究领域：Osteoarthritis Treatment and Mechanisms、Bone Tissue Engineering Materials、Silk-based biomaterials and applications

: The GM-HPCH + TGFβ1 hydrogel effectively promoted cartilage repair via immunomodulating macrophages, recruiting MSCs and promoting chondrogenesis; thus it is a promising injectable hydrogel for cartilage regeneration.