Endocannabinoid genetic variation enhances vulnerability to THC reward in adolescent female mice

作者：Caitlin E. Burgdorf, Deqiang Jing, Ruirong Yang, Chienchun Huang, Matthew N. Hill, Ken Mackie, Teresa A. Milner, Virginia M. Pickel, Francis S. Lee, Anjali M. Rajadhyaksha · 发表于：Science Advances · 年份：2020 · DOI：10.1126/sciadv.aay1502 · 被引用次数：31 · 研究领域：Cannabis and Cannabinoid Research、Diet, Metabolism, and Disease、Neurotransmitter Receptor Influence on Behavior

mice to THC preference that persists into adulthood. Together, these findings suggest that this endocannabinoid genetic variant is a contributing factor for increased susceptibility to cannabis dependence in adolescent females.