Global, regional, and national burden of chronic kidney disease, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017

作者：Boris Bikbov, Caroline Purcell, Andrew S. Levey, Mari Smith, Amir Abdoli, Molla Abebe, Oladimeji Adebayo, Mohsen Afarideh, Sanjay Kumar Agarwal, Marcela Agudelo‐Botero, Elham Ahmadian, Ziyad Al‐Aly, Vahid Alipour, Amir Almasi‐Hashiani, Rajaa Al‐Raddadi, Nelson Alvis‐Guzmán, Saeed Amini, Tudorel Andrei, Cătălina Liliana Andrei, Zewudu Andualem, Mina Anjomshoa, Jalal Arabloo, Alebachew Fasil Ashagre, Daniel Asmelash, Zerihun Ataro, Maha Atout, Martin Amogre Ayanore, Alaa Badawi, Ahad Bakhtiari, Shoshana H. Ballew, Abbas Balouchi, Maciej Banach, Sı́món Barquera, Sanjay Basu, Mulat Tirfie Bayih, Neeraj Bedi, Aminu K. Bello, Isabela M. Benseñor, Ali Bijani, Archith Boloor, Antonio Maria Borzì, Luis Alberto Cámera, Juan Jesús Carrero, Félix Carvalho, Franz Castro, Ferrán Catalá-López, Alex R. Chang, Ken Lee Chin, Sheng‐Chia Chung, Massimo Círillo, Ewerton Cousin, Lalit Dandona, Rakhi Dandona, Ahmad Daryani, Rajat Das Gupta, Feleke Mekonnen Demeke, Gebre Teklemariam Demoz, Desilu Mahari Desta, Huyen Phuc, Bruce Bartholow Duncan, Aziz Eftekhari, Alireza Esteghamati, Syeda Sadia Fatima, João Carlos Fernandes, Eduarda Fernandes, Florian Fischer, Marisa Freitas, Mohamed M. Gad, Gebreamlak Gebremedhn Gebremeskel, Begashaw Melaku Gebresillassie, Birhanu Geta, Mansour Ghafourifard, Alireza Ghajar, Nermin Ghith, Paramjit Gill, Ibrahim Ginawi, Rajeev Gupta, Nima Hafezi‐Nejad, Arvin Haj‐Mirzaian, Arya Haj‐Mirzaian, Ninuk Hariyani, Mehedi Hasan, Milad Hasankhani, Amir Hasanzadeh, Hamid Yimam Hassen, Simon I Hay, Behnam Heidari, Claudiu Herţeliu, Chi Linh Hoang, Mostafa Hosseini, Mihaela Hostiuc, Seyed Sina Naghibi Irvani, Sheikh Mohammed Shariful Islam, Nader Jafari Balalami, Spencer L James, Simerjot K Jassal, Vivekanand Jha, Jost B Jonas, Farahnaz Joukar, Jacek Jerzy Jozwiak, Ali Kabir, Amaha Kahsay, Amir Kasaeian, Tesfaye Kassa, Hagazi Gebremedhin Kassaye, Yousef Khader, Rovshan Khalilov, Ejaz Ahmad Khan, Mohammad Saud Khan, Young‐Ho Khang, Adnan Kısa, Csaba P. Kövesdy, Barthélémy Kuate Defo, G Anil Kumar, Anders Larsson, Lee‐Ling Lim, Alan D Lopez, Paulo A. Lotufo, Azeem Majeed, Reza Malekzadeh, Winfried März, Anthony Masaka, Hailemariam Abiy Alemu Meheretu, Tomasz Miazgowski, Andreea Mirică, Erkin М Мirrakhimov, Prasanna Mithra, Babak Moazen, Dara K. Mohammad, Reza Mohammadpourhodki, Shafiu Mohammed, Ali H. Mokdad, Linda Morales, Ilais Moreno Velásquez, Seyyed Meysam Mousavi, Satinath Mukhopadhyay, Jean B. Nachega, Girish N. Nadkarni, Jobert Richie Nansseu, Gopalakrishnan Natarajan, Javad Nazari, Bruce Neal, Ruxandra Irina Negoi, Cuong Tat Nguyen, Rajan Nikbakhsh, Jean Jacques Noubiap, Christoph Nowak, Andrew T Olagunju, Alberto Ortíz, Mayowa Owolabi, Raffaele Palladino, Mona Pathak, Hossein Poustchi, Swayam Prakash, Narayan Prasad, Alireza Rafiei, Sree Bhushan Raju, Kiana Ramezanzadeh, Salman Rawaf, David Laith Rawaf, Lal Rawal, Robert C. Reiner, Aziz Rezapour, Daniel Cury Ribeiro, Leonardo Roever, Dietrich Rothenbacher, Godfrey Mutashambara Rwegerera, Seyedmohammad Saadatagah, Saeed Safari, Berhe W. Sahle, Hosni A Salem, Juan Sanabria, Itamar S Santos, Arash Sarveazad, Monika Sawhney, Elke Schäeffner, María Inês Schmidt, Aletta E. Schutte, Sadaf G Sepanlou, Masood Ali Shaikh, Zeinab Sharafi, Mehdi Sharif, Amrollah Sharifi, Diego Augusto Santos Silva, Jasvinder A. Singh, Narinder Pal Singh, Malede Mequanent Sisay, Amin Soheili, Ipsita Sutradhar, Berhane Fseha Teklehaimanot, Berhe Etsay Tesfay, Getnet Teshome, Jarnail Singh Thakur, Marcello Tonelli, Khanh Bao Tran, Bach Xuan Tran, Candide Tran Ngoc, Irfan Ullah, Pascual Valdéz, Santosh Varughese, Theo Vos, Linh Gia Vu, Yasir Waheed, Andrea Werdecker, Haileab Fekadu Wolde, Adam Wondmieneh, Sarah Wulf Hanson, Tomohide Yamada, Yigizie Yeshaw, Naohiro Yonemoto, Hasan Yusefzadeh, Zoubida Zaidi, Leila Zaki, Sojib Bin Zaman, Nelson Zamora, Afshin Zarghi, Kaleab Alemayehu Zewdie, Johan Ärnlöv, Josef Coresh, Norberto Perico, Giuseppe Remuzzi, Chris Murray, Theo Vos · 发表于：The Lancet · 年份：2020 · DOI：10.1016/s0140-6736(20)30045-3 · 被引用次数：6812 · 研究领域：Chronic Kidney Disease and Diabetes、Gout, Hyperuricemia, Uric Acid、Acute Kidney Injury Research

BACKGROUND: Health system planning requires careful assessment of chronic kidney disease (CKD) epidemiology, but data for morbidity and mortality of this disease are scarce or non-existent in many countries. We estimated the global, regional, and national burden of CKD, as well as the burden of cardiovascular disease and gout attributable to impaired kidney function, for the Global Burden of Diseases, Injuries, and Risk Factors Study 2017. We use the term CKD to refer to the morbidity and mortality that can be directly attributed to all stages of CKD, and we use the term impaired kidney function to refer to the additional risk of CKD from cardiovascular disease and gout. METHODS: The main data sources we used were published literature, vital registration systems, end-stage kidney disease registries, and household surveys. Estimates of CKD burden were produced using a Cause of Death Ensemble model and a Bayesian meta-regression analytical tool, and included incidence, prevalence, years lived with disability, mortality, years of life lost, and disability-adjusted life-years (DALYs). A comparative risk assessment approach was used to estimate the proportion of cardiovascular diseases and gout burden attributable to impaired kidney function. FINDINGS: Globally, in 2017, 1·2 million (95% uncertainty interval [UI] 1·2 to 1·3) people died from CKD. The global all-age mortality rate from CKD increased 41·5% (95% UI 35·2 to 46·5) between 1990 and 2017, although there was no significan...