Rapid non-uniform adaptation to conformation-specific KRAS(G12C) inhibition

作者：Jenny Y. Xue, Yulei Zhao, Jordan Aronowitz, Trang T. Mai, Alberto Vides, Besnik Qeriqi, Dong-Sung Kim, Chuanchuan Li, Elisa de Stanchina, Linas Mažutis, Davide Risso, Piro Lito · 发表于：Nature · 年份：2020 · DOI：10.1038/s41586-019-1884-x · 被引用次数：564 · 研究领域：Protein Kinase Regulation and GTPase Signaling、Cellular Mechanics and Interactions、Melanoma and MAPK Pathways