Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer’s disease

作者：Yingyue Zhou, Wilbur M. Song, Prabhakar S. Andhey, Amanda Swain, Tyler Levy, Kelly R. Miller, Pietro Luigi Poliani, Manuela Cominelli, Shikha Grover, Susan Gilfillan, Marina Cella, Tyler K. Ulland, Konstantin Zaitsev, Akinori Miyashita, Takeshi Ikeuchi, Makoto Sainouchi, Akiyoshi Kakita, David A. Bennett, Julie A. Schneider, Michael R. Nichols, Sean A. Beausoleil, Jason D. Ulrich, David M. Holtzman, Maxim N. Artyomov, Marco Colonna · 发表于：Nature Medicine · 年份：2020 · DOI：10.1038/s41591-019-0695-9 · 被引用次数：1229 · 研究领域：Neuroinflammation and Neurodegeneration Mechanisms、Inflammation biomarkers and pathways、Medicinal Plants and Neuroprotection