[Study on neoflavonoids from heartwood of Dalbergia latifolia].

作者：Xiaowei Meng, Ding-qing Wang, Lanying Chen, Feng Shao, Puzhao Zhang, Shao-Jie Hu, Qing Zhu, Ronghua Liu · 发表于：PubMed · 年份：2019 · DOI：10.19540/j.cnki.cjcmm.20181228.002 · 被引用次数：5 · 研究领域：Traditional Chinese Medicine Analysis、Medicinal Plant Pharmacodynamics Research、Chromatography in Natural Products

Dalbergiae Odoriferae Lignum is derived from heartwood of Dalbergia odorifera,which is national Ⅱ level of rare and endangered protective plants in China. Its resources are scarce and its price is high. In order to find substitutes of D. odorifera,the chemical constituents of 70% ethanol extract of heartwood of D. catifolia were systematically studied by using silica gel,Sephadex LH-20 column chromatography,and semi-preparative HPLC. Sixteen neoflavanoids were isolated and identified as eight dalbergiphenols( 1-8),three dalbergiones( 9-11),two dalbergins( 12,13),two benzophenones( 14,15) and one other type neoflavanoids( 16) based on spectroscopic data analyses and/or comparing the spectroscopic data with those in literature. Among them,compounds 3,7 and 11 were isolated from the genus Dalbergia for the first time,and compounds 2,4-6,8,14 and 15 were isolated from the D. latifolia for the first time. Ten neoflavonoids were both discovered from D. latifolia and D. odorifera.