Donor–acceptor conjugated polymer-based nanoparticles for highly effective photoacoustic imaging and photothermal therapy in the NIR-II window

作者：Zuwu Wei, Fuli Xin, Jian Zhang, Ming Wu, Ting Qiu, Yintao Lan, Shuangying Qiao, Xiaolong Liu, Jingfeng Liu · 发表于：Chemical Communications · 年份：2019 · DOI：10.1039/c9cc07821e · 被引用次数：80 · 研究领域：Nanoplatforms for cancer theranostics、Photoacoustic and Ultrasonic Imaging、Gold and Silver Nanoparticles Synthesis and Applications

We prepared novel conjugated polymer based NIR-II nanoparticles, which display extremely high photothermal conversion efficiency (65%). Both in vitro and in vivo investigations revealed that the as-prepared nanoparticles exhibit excellent theranostic properties including an extremely high cancer cell killing ability, admirable tumor elimination efficiency (100%) and a remarkable photoacoustic imaging contrast enhancing ability.