The burden of mental disorders across the states of India: the Global Burden of Disease Study 1990–2017

作者：Rajesh Sagar, Rakhi Dandona, Gopalkrishna Gururaj, Rupinder Singh Dhaliwal, Aditya Singh, Alize J Ferrari, Tarun Dua, Atreyi Ganguli, Mathew Varghese, Joy Kumar Chakma, G Anil Kumar, K S Shaji, Atul Ambekar, R. Thara, Lakshmi Vijayakumar, Vivek Agarwal, Rinu P Krishnankutty, Rohit Bhatia, Fiona Charlson, Neerja Chowdhary, Holly E Erskine, Scott Glenn, Varsha Krish, Ana Maria Mantilla Herrera, Parul Mutreja, Christopher M Odell, Pramod Kumar Pal, Sanjay Prakash, Damian Santomauro, Deeksha Shukla, Ravinder Singh, Ragini Singh, JS Thakur, Akhil Soman ThekkePurakkal, Chris M Varghese, K. Srinath Reddy, Soumya Swaminathan, Harvey Whiteford, Hendrik J Bekedam, Christopher J L Murray, Theo Vos, Lalit Dandona · 发表于：The Lancet Psychiatry · 年份：2019 · DOI：10.1016/s2215-0366(19)30475-4 · 被引用次数：896 · 研究领域：Mental Health Treatment and Access、Schizophrenia research and treatment、Bipolar Disorder and Treatment

BACKGROUND: Mental disorders are among the leading causes of non-fatal disease burden in India, but a systematic understanding of their prevalence, disease burden, and risk factors is not readily available for each state of India. In this report, we describe the prevalence and disease burden of each mental disorder for the states of India, from 1990 to 2017. METHODS: We used all accessible data from multiple sources to estimate the prevalence of mental disorders, years lived with disability (YLDs), and disability-adjusted life-years (DALYs) caused by these disorders for all the states of India from 1990 to 2017, as part of the Global Burden of Diseases, Injuries, and Risk Factors Study. We assessed the heterogeneity and time trends of mental disorders across the states of India. We grouped states on the basis of their Socio-demographic Index (SDI), which is a composite measure of per-capita income, mean education, and fertility rate in women younger than 25 years. We also assessed the association of major mental disorders with suicide deaths. We calculated 95% uncertainty intervals (UIs) for the point estimates. FINDINGS: =0·19, p=0·015). The contribution of mental disorders to the total DALYs in India increased from 2·5% (2·0-3·1) in 1990 to 4·7% (3·7-5·6) in 2017. In 2017, depressive disorders contributed the most to the total mental disorders DALYs (33·8%, 29·5-38·5), followed by anxiety disorders (19·0%, 15·9-22·4), idiopathic developmental intellectual disability (IDID; ...