Visible-Light-Enabled Oxidative Coupling of Alkenes with Dialkylformamides To Access Unsaturated Amides

作者：Maojian Lu, Zhaowei Lin, Shanyi Chen, Hong-You Chen, Mingqiang Huang, Shunyou Cai · 发表于：Organic Letters · 年份：2019 · DOI：10.1021/acs.orglett.9b03870 · 被引用次数：21 · 研究领域：Radical Photochemical Reactions、Sulfur-Based Synthesis Techniques、Catalytic C–H Functionalization Methods

A practical and direct method for oxidative cross-coupling of alkenes with dialkylformamides is established employing visible-light-enabled photoredox catalysis. This strategy allows efficient access to diverse unsaturated amides under mild reaction conditions. The application of an appropriate diaryliodonium salt was demonstrated to be critical to the success of this process. This catalyst system is well tolerant of a variety of useful functional groups.