Targeting the STING pathway in tumor-associated macrophages regulates innate immune sensing of gastric cancer cells

作者：Lei Miao, Jingjing Qi, Qi Zhao, Qi-Nian Wu, Da‐Liang Wei, Xiao-Li Wei, Jia Liu, Jun Chen, Zhao-Lei Zeng, Huai‐Qiang Ju, Hui Luo, Rui‐Hua Xu · 发表于：Theranostics · 年份：2019 · DOI：10.7150/thno.37745 · 被引用次数：189 · 研究领域：interferon and immune responses、Immune cells in cancer、Inflammasome and immune disorders

: This study evaluated effects of targeting STING in TAMs in anti-gastric-cancer therapies. Moreover, we unveil a novel function of STING to activate the IL6R-JAK-IL24 pathway in macrophages.