c-Jun overexpression in CAR T cells induces exhaustion resistance

作者：Rachel C. Lynn, Evan W. Weber, Elena Sotillo, David G. Gennert, Peng Xu, Zinaida Good, Hima Anbunathan, John Lattin, Robert Christopher Jones, Victor Tieu, Surya Nagaraja, Jeffrey M. Granja, Charles F. A. de Bourcy, Robbie G. Majzner, Ansuman T. Satpathy, Stephen R. Quake, Michelle Monje, Howard Y. Chang, Crystal Lee Mackall · 发表于：Nature · 年份：2019 · DOI：10.1038/s41586-019-1805-z · 被引用次数：923 · 研究领域：CAR-T cell therapy research、Immune Cell Function and Interaction、T-cell and B-cell Immunology