Circular ecDNA promotes accessible chromatin and high oncogene expression

作者：Sihan Wu, Kristen M. Turner, Nam Nguyen, Ramya Raviram, Marcella L. Erb, Jennifer Santini, Jens Luebeck, Utkrisht Rajkumar, Yarui Diao, Bin Li, Wenjing Zhang, Nathan M. Jameson, M. Ryan Corces, Jeffrey M. Granja, Xingqi Chen, Ceyda Çoruh, Armen Abnousi, Jack Houston, Zhen Ye, Rong Hu, Miao Yu, Hoon Kim, Julie A. Law, Roel G.W. Verhaak, Ming Hu, Frank B. Furnari, Howard Y. Chang, Bing Ren, Vineet Bafna, Paul S. Mischel · 发表于：Nature · 年份：2019 · DOI：10.1038/s41586-019-1763-5 · 被引用次数：732 · 研究领域：Cancer Genomics and Diagnostics、Genomics and Chromatin Dynamics、RNA modifications and cancer