Ensembl Genomes 2020—enabling non-vertebrate genomic research

作者：Kevin Howe, Bruno Contreras‐Moreira, Nishadi De Silva, G. Maslen, Wasiu Akanni, James E. Allen, Jorge Álvarez-Jarreta, Matthieu Barba, Dan Bolser, Lahcen Cambell, Manuel Carbajo Martinez, Marc Chakiachvili, Mikkel Christensen, Carla Cummins, Alayne Cuzick, Paul A. Davis, Silvie Fexová, Astrid Gall, Nancy George, Laurent Gil, Parul Gupta, K. E. Hammond‐Kosack, Erin Haskell, Sarah Hunt, Pankaj Jaiswal, Sophie H. Janacek, Paul Kersey, Nicholas Langridge, Uma Maheswari, Thomas Maurel, Mark D. McDowall, Benjamin Moore, Matthieu Muffato, Guy Naamati, Sushma Naithani, Andrew Olson, Irene Papatheodorou, Mateus Patrício, Michael Paulini, Helder Pedro, Emily Perry, Justin Preece, Marc Rosello, Matthew Russell, Vasily Sitnik, D. Staines, Joshua C. Stein, Marcela K Tello-Ruiz, Stephen J. Trevanion, Martin Urban, Sharon Wei, Doreen Ware, Gary W. Williams, Andrew Yates, Paul Flicek · 发表于：Nucleic Acids Research · 年份：2019 · DOI：10.1093/nar/gkz890 · 被引用次数：535 · 研究领域：Genomics and Phylogenetic Studies、Chromosomal and Genetic Variations、Genetic Mapping and Diversity in Plants and Animals

Ensembl Genomes (http://www.ensemblgenomes.org) is an integrating resource for genome-scale data from non-vertebrate species, complementing the resources for vertebrate genomics developed in the context of the Ensembl project (http://www.ensembl.org). Together, the two resources provide a consistent set of interfaces to genomic data across the tree of life, including reference genome sequence, gene models, transcriptional data, genetic variation and comparative analysis. Data may be accessed via our website, online tools platform and programmatic interfaces, with updates made four times per year (in synchrony with Ensembl). Here, we provide an overview of Ensembl Genomes, with a focus on recent developments. These include the continued growth, more robust and reproducible sets of orthologues and paralogues, and enriched views of gene expression and gene function in plants. Finally, we report on our continued deeper integration with the Ensembl project, which forms a key part of our future strategy for dealing with the increasing quantity of available genome-scale data across the tree of life.