[Etiologies and risk factors for young people with intracerebral hemorrhage].

作者：Wenwen Li, Qiying Sun, Duan Xian, Fang Yi, Yafang Zhou, Yacen Hu, Lingyan Yao, Hongwei Xu, Lin Zhou · 发表于：PubMed · 年份：2018 · DOI：10.11817/j.issn.1672-7347.2018.11.013 · 被引用次数：16 · 研究领域：Intracerebral and Subarachnoid Hemorrhage Research、Moyamoya disease diagnosis and treatment

OBJECTIVE: To determine the etiologies and risk factors of intracerebral hemorrhage in young people. Methods: A total of 401 young patients with intracerebral hemorrhage were enrolled, and they were assigned into a 20-29 , a 30-39, and a 40-45 age group. The differences of various etiologies and risk factors among the three groups were analyzed. Results: There were 273 men and 128 women in the 401 young patients. The etiologies of 294 patients (73.32%) were identified while 107 patients (26.68%) were unknown. Among those with identified etiology, 226 patients (56.36%) suffered from hypertension, 41 patients (10.22%) congenital cerebrovascular malformation (including 25 patients with cerebral arteriovenous malformation, 8 intracranial cavernous hemangioma, and 8 intracranial aneurysm), and 27 other etiologies (including 9 patients with moyamoya disease, 6 cerebral venous sinus thrombosis, 4 drug abuse, 3 hemorrhagic brain tumor, 2 intracranial infection, 1 systemic lupus erythematosus, 1 drug-induced, and 1 eclampsia). Risk factors included hypertension (237 cases, 59.10%), smoking (123 cases, 30.67%), alcohol consumption (74 cases, 18.45%), and others (19 cases, 4.74%; including 8 cases of pregnancy or in the puerperium, 8 family history of intracerebral hemorrhage, and 3 taking anti-platelet aggregation/anticoagulation agents). The rate of hypertension induced hemorrhage significantly increased with age (P<0.01); the rate of vascular malformations in 20-29 age group was obvi...