Survival Outcomes of Mucosal Melanoma in the USA

作者：Ali Al‐Haseni, Abby Vrable, Muhammad Mustafa Qureshi, Stephanie Mathews, Samara Pollock, M.T. Truong, Debjani Sahni · 发表于：Future Oncology · 年份：2019 · DOI：10.2217/fon-2019-0465 · 被引用次数：26 · 研究领域：Cutaneous Melanoma Detection and Management、Nonmelanoma Skin Cancer Studies、Melanoma and MAPK Pathways

Background: Mucosal melanomas (MM) arise within the lining of the gastrointestinal (GI), genitourinary (GU) and head and neck (HN) systems. Method: A retrospective analysis of the National Comprehensive Database identified 4,961 MM patients. Primary objective was to compare survival outcomes across the different locations. Results: Overall survival for GI melanomas was significantly shorter than HN and GU melanomas. Median survival (95% confidence interval) was 19.5 (18.0–21.5), 26.4 (24.9–28.3), and 43.9 (38.8–47.8), months for GI, HN and GU cases, respectively (p<0.0001). Conclusion: This is the largest study of MM in a US based population, demonstrating worse overall survival for GI MM in comparison to HN and GU melanomas.