Meningococcal Quinolone Resistance Originated from Several Commensal Neisseria Species

作者：Mingliang Chen, Chi Zhang, Xi Zhang, Min Chen · 发表于：Antimicrobial Agents and Chemotherapy · 年份：2019 · DOI：10.1128/aac.01494-19 · 被引用次数：67 · 研究领域：Bacterial Infections and Vaccines、Escherichia coli research studies、Pneumonia and Respiratory Infections

Quinolone resistance is increasing in Neisseria meningitidis , with its prevalence in China being high (>70%), but its origin remains unknown. The aim of this study was to investigate the donors of mutation-harboring gyrA alleles in N. meningitidis . A total of 198 N. meningitidis isolates and 293 commensal Neisseria isolates were collected between 2005 and 2018 in Shanghai, China. The MICs of ciprofloxacin were determined using the agar dilution method.