When All Else Fails: Novel Use of Angiotensin II for Vasodilatory Shock: A Case Report

作者：Jonathan H. Chow, Samuel M. Galvagno, Kenichi A. Tanaka, Michael A. Mazzeffi, Zackary Chancer, Reney Henderson, Michael T. McCurdy · 发表于：A&A Practice · 年份：2018 · DOI：10.1213/xaa.0000000000000775 · 被引用次数：27 · 研究领域：Sepsis Diagnosis and Treatment、Hemodynamic Monitoring and Therapy、Renal function and acid-base balance

Angiotensin (AT) II is an endogenous hormone that acts on venous and arterial smooth muscle to cause vasoconstriction. Recent trials have sparked great interest in its ability to be used as a vasopressor for catecholamine-refractory hypotension. Herein, we describe the successful use of AT II in a patient with a colonic perforation with septic shock refractory to conventional treatment. After AT II initiation, there was an immediate reduction in catecholamine requirement, and the patient survived.