ROS-dependent DNA damage contributes to crizotinib-induced hepatotoxicity via the apoptotic pathway

作者：Hao Yan, Jiangxia Du, Xueqin Chen, Bo Yang, Qiaojun He, Xiaochun Yang, Peihua Luo · 发表于：Toxicology and Applied Pharmacology · 年份：2019 · DOI：10.1016/j.taap.2019.114768 · 被引用次数：48 · 研究领域：Lung Cancer Treatments and Mutations、PI3K/AKT/mTOR signaling in cancer、Cancer Mechanisms and Therapy