Self-Expanded Metallic Stent Insertion for Hilar Cholangiocarcinoma: Comparison of Unilateral and Bilateral Stenting

作者：Xue Yin, Dongmei Li, Fang Yang, Tonggang Liu, Feng-Fei Xia, Yu‐Fei Fu · 发表于：Journal of Laparoendoscopic & Advanced Surgical Techniques · 年份：2019 · DOI：10.1089/lap.2019.0509 · 被引用次数：25 · 研究领域：Cholangiocarcinoma and Gallbladder Cancer Studies、Gallbladder and Bile Duct Disorders、Pediatric Hepatobiliary Diseases and Treatments

Abstract Purpose: This study aims to ascertain the relative outcomes in patients with hilar cholangiocarcinoma (HCCA) undergoing either unilateral or bilateral self-expanded metallic stent (SEMS) insertion. Materials and Methods: In this retrospective single-center study, 93 patients with HCCA were treated through percutaneous insertion of either unilateral or bilateral SEMS during January 2012 to December 2018. We compared technical success, clinical success, and long-term outcomes of the treatment method. Results: Overall, 51 and 42 patients were treated through unilateral and bilateral SEMS insertion, respectively, with technical success rates of 92.2% (47/51) and 95.3% (40/42), respectively, ( P = .859). No patients experienced any procedure-related complications, with unilateral and bilateral clinical success rates of 95.7% (45/47) and 97.4% (38/39), respectively, ( P = 1.000) and with comparable adverse event rates between these groups (3/47 vs. 5/40; P = .541). Moreover, 8 and 3 patients treated with unilateral and bilateral stents exhibited stent dysfunction, respectively, ( P = .183). In unilateral and bilateral groups, median patency rates were189 and 198 days, respectively, ( P = .887). During the follow-up period, all patients died, with respective mean overall survival rates of 222 and 202 days for those treated using unilateral and bilateral stents ( P = .755). Both Bismuth type III HCCA ( P = .025) and a lack of chemotherapy ( P = .000) correlated with reduced ...