High In Vitro Susceptibility to the First-in-Class Spiropyrimidinetrione Zoliflodacin among Consecutive Clinical Neisseria gonorrhoeae Isolates from Thailand and South Africa

作者：Susanne Jacobsson, Ranmini Kularatne, Rossaphorn Kittiyaowamarn, Venessa Maseko, Porntip Paopang, Pongsathorn Sangprasert, Pachara Sirivongrangson, Laura J. V. Piddock, Teodora Wi, Emilie Alirol, Magnus Unemo · 发表于：Antimicrobial Agents and Chemotherapy · 年份：2019 · DOI：10.1128/aac.01479-19 · 被引用次数：21 · 研究领域：Reproductive tract infections research、Bacterial Infections and Vaccines、Reproductive Health and Contraception

: 0.125 μg/ml), with no cross-resistance to any of the seven comparator antimicrobials. Our data support the initiation of the global zoliflodacin phase 3 randomized controlled clinical trial for uncomplicated gonorrhea.