Ciliated muconodular papillary tumor of the lung: report of two cases and review of the literature

作者：Leilei Shen, Jixing Lin, Zhipeng Ren, Bailin Wang, Kai Zhao, Yunlong Lu, Fulin Wang, Lianbin Zhan · 发表于：Journal of Surgical Case Reports · 年份：2019 · DOI：10.1093/jscr/rjz247 · 被引用次数：11 · 研究领域：Medical Imaging and Pathology Studies、Tracheal and airway disorders、Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

Ciliated muconodular papillary tumor (CMPT) is a peripheral non-endobronchial lung nodule, consisting of ciliated columnar cells and goblet cells with basaloid cell proliferation. Only about 50 cases confirmed by surgery have been reported in English literature worldwide. We present two surgical cases of CMPT in this report. Two patients presented with abnormal computed tomography findings but no obvious symptoms. The first patient's intraoperative frozen examination was unable to distinguish benignity from malignancy, and he received lobectomy. The other patient's intraoperative frozen examination indicated adenocarcinoma, but she received wedge resection for her refusal to lobectomy. The two patients' postoperative pathological analysis finally confirmed the diagnosis of CMPT. We believe that our cases may be essential for pathologists and surgeons to improve their understanding.