Effect of laparoscopic myomectomy on serum levels of IL‑6 and TAC, and ovarian function

作者：Yanling Hu, Liyao Yu, Xia Fen, Fengqi Liang, Chao Cheng, Yuhua Huang, Linqi Xiao · 发表于：Experimental and Therapeutic Medicine · 年份：2019 · DOI：10.3892/etm.2019.7941 · 被引用次数：8 · 研究领域：Uterine Myomas and Treatments、Endometriosis Research and Treatment、Gynecological conditions and treatments

Effect of laparoscopic myomectomy on the serum levels of interleukin‑6 (IL‑6) and total antioxidant capacity (TAC), and the ovarian function of patients with uterine fibroids was studied. Ninety patients with uterine fibroids admitted to The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, from March 2013 to July 2014, were randomly divided into the experimental group (n=45) and the control group (n=45). The experimental group was treated with laparoscopic myomectomy, and the control group was treated with abdominal myomectomy. ELISA was used for detecting IL‑6 and TAC content. Radioimmunoassay (RIA) was used for detecting serum ovarian function indicators, including estradiol (E2), follicle‑stimulating hormone (FSH) and luteinizing hormone (LH). Patients in the experimental group had significantly lower intraoperative blood loss, postoperative exhaust time, number of days to recovery and return to work, number of intraoperative fibroids removed, and length of stay than those in the control group (P<0.05). TAC expression level was significantly higher in the experimental group than that in the control group, on the 1st, 3rd and 5th day after surgery (P<0.05), while IL‑6 expression was significantly lower in the experimental group than that in the control group at the same time points (P<0.05). FSH and LH expression levels were significantly lower in the experimental group than those in the control group (P<0.05) at 1, 3 and 6 m...