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DNA methylation-based estimator of telomere length

作者:Ake T. Lu, Anne Seeboth, Pei-Chien Tsai, Dianjianyi Sun, Austin Quach, Alex P. Reiner, Charles Kooperberg, Luigi Ferrucci, Lifang Hou, Andrea Baccarelli, Yun Li, Sarah E. Harris, Janie Corley, Adele Taylor, Ian J. Deary, James D. Stewart, Eric A. Whitsel, Themistocles L. Assimes, Wei Chen, Shengxu Li, Massimo Mangino, Jordana T. Bell, James G. Wilson, Abraham Aviv, Riccardo E. Marioni, Kenneth Raj, Steve Horvath · 发表于:Aging · 年份:2019 · DOI:10.18632/aging.102173 · 被引用次数:477 · 研究领域:Epigenetics and DNA Methylation、Telomeres, Telomerase, and Senescence、Birth, Development, and Health

. DNAmTL is not only an epigenetic biomarker of replicative history of cells, but a useful marker of age-related pathologies that are associated with it.