Sleep, circadian rhythm, and physical activity patterns in depressive and anxiety disorders: A 2‐week ambulatory assessment study

作者：Sonia Difrancesco, Femke Lamers, Harriëtte Riese, Kathleen R. Merikangas, Aartjan T.F. Beekman, Albert M. van Hemert, Robert A. Schoevers, Brenda W.J.H. Penninx · 发表于：Depression and Anxiety · 年份：2019 · DOI：10.1002/da.22949 · 被引用次数：232 · 研究领域：Sleep and related disorders、Physical Activity and Health、Circadian rhythm and melatonin

BACKGROUND: Actigraphy may provide a more valid assessment of sleep, circadian rhythm (CR), and physical activity (PA) than self-reported questionnaires, but has not been used widely to study the association with depression/anxiety and their clinical characteristics. METHODS: Fourteen-day actigraphy data of 359 participants with current (n = 93), remitted (n = 176), or no (n = 90) composite international diagnostic interview depression/anxiety diagnoses were obtained from the Netherlands Study of Depression and Anxiety. Objective estimates included sleep duration (SD), sleep efficiency, relative amplitude (RA) between day-time and night-time activity, mid sleep on free days (MSF), gross motor activity (GMA), and moderate-to-vigorous PA (MVPA). Self-reported measures included insomnia rating scale, SD, MSF, metabolic equivalent total, and MVPA. RESULTS: Compared to controls, individuals with current depression/anxiety had a significantly different objective, but not self-reported, PA and CR: lower GMA (23.83 vs. 27.4 milli-gravity/day, p = .022), lower MVPA (35.32 vs. 47.64 min/day, p = .023), lower RA (0.82 vs. 0.83, p = .033). In contrast, self-reported, but not objective, sleep differed between people with current depression/anxiety compared to those without current disorders; people with current depression/anxiety reported both shorter and longer SD and more insomnia. More depressive/anxiety symptoms and number of depressive/anxiety diagnoses were associated with larger di...