Annual Incidence of Adult and Pediatric In-Hospital Cardiac Arrest in the United States

作者：Mathias Johan J Holmberg, Catherine E. Ross, Garrett M. Fitzmaurice, Paul S. Chan, Jordan Duval‐Arnould, Anne Victoria Grossestreuer, Tuyen T. Yankama, Michael W. Donnino, Lars W. Andersen, Paul S. Chan, Anne Victoria Grossestreuer, Ari L. Moskowitz, Dana P. Edelson, Joseph P. Ornato, Katherine Berg, Mary Ann Peberdy, Matthew M. Churpek, Michael Christopher Kurz, Monique Anderson Starks, Saket R. Girotra, Sarah Perman, Zachary D. Goldberger, Anne‐Marie Guerguerian, Dianne L. Atkins, Elizabeth E. Foglia, Ericka L. Fink, Javier J. Lasa, Joan S. Roberts, Melanie Bembea, Michael Gaies, Monica E. Kleinman, Punkaj Gupta, Robert Michael Sutton, Taylor Sawyer · 发表于：Circulation Cardiovascular Quality and Outcomes · 年份：2019 · DOI：10.1161/circoutcomes.119.005580 · 被引用次数：487 · 研究领域：Cardiac Arrest and Resuscitation、Sepsis Diagnosis and Treatment、Mechanical Circulatory Support Devices

BACKGROUND: Previous incidence estimates may no longer reflect the current public health burden of cardiac arrest in hospitalized adult and pediatric patients across the United States. The aim of this study was to estimate the contemporary annual incidence of in-hospital cardiac arrest in adults and children across the United States and to describe trends in incidence between 2008 and 2017. METHODS AND RESULTS: Using the Get With The Guidelines– Resuscitation registry, we developed a negative binomial regression model to estimate the incidence of index pulseless in-hospital cardiac arrest based on hospital-level characteristics. The model was used to predict the number of in-hospital cardiac arrests in all US hospitals, using data from the American Hospital Association Annual Survey. We performed separate analyses for adult (≥18 years) and pediatric (<18 years) cardiac arrests. Additional analyses were performed for recurrent cardiac arrests and pediatric patients requiring cardiopulmonary resuscitation for poor perfusion (nonpulseless events). The average annual incidence of in-hospital cardiac arrest in the United States was estimated at 292 000 (95% prediction interval, 217 600–503 500) adult and 15 200 pediatric cases, of which 7100 (95% prediction interval, 4400–9900) cases were pulseless cardiac arrests and 8100 (95% prediction interval, 4700–11 500) cases were nonpulseless events. The rate of adult cardiac arrests increased over time, while pediatric events remained mo...