A Compound AC1Q3QWB Selectively Disrupts HOTAIR-Mediated Recruitment of PRC2 and Enhances Cancer Therapy of DZNep

作者：Yansheng Li, Yu Ren, Yunfei Wang, Yanli Tan, Qixue Wang, Jinquan Cai, Junhu Zhou, Chao Yang, Kai Zhao, Kaikai Yi, Weili Jin, Lin Wang, Mingyang Liu, Jingxuan Yang, Min Li, Chunsheng Kang · 发表于：Theranostics · 年份：2019 · DOI：10.7150/thno.35188 · 被引用次数：99 · 研究领域：Cancer-related molecular mechanisms research、RNA modifications and cancer、RNA Research and Splicing

AQB is a HOTAIR-EZH2 inhibitor, which blocks PRC2 recruitment and has great potential as an effective agent for targeted cancer therapy.