Verbal fluency as a screening tool for mild cognitive impairment

作者：Michelle McDonnell, Lauren Dill, Stella E. Panos, Stacy Amano, Warren S. Brown, Shadee Giurgius, Gary W. Small, Karen Miller · 发表于：International Psychogeriatrics · 年份：2019 · DOI：10.1017/s1041610219000644 · 被引用次数：116 · 研究领域：Dementia and Cognitive Impairment Research、Neurobiology of Language and Bilingualism、Dysphagia Assessment and Management

OBJECTIVES: The goal of this study was to evaluate the ability of semantic (animal naming) and phonemic (FAS) fluency in their ability to discriminate between normal aging, amnestic-Mild Cognitive Impairment (a-MCI), and Alzheimer's disease (AD). DESIGN: We used binary logistic regressions, multinomial regressions, and discriminant analysis to evaluate the predictive value of semantic and phonemic fluency in regards to specific diagnostic classifications. SETTING: Outpatient geriatric neuropsychology clinic. PARTICIPANTS: 232 participants (normal aging = 99, a-MCI = 90, AD = 43; mean age = 65.75 years). MEASUREMENTS: Mini-mental State Examination (MMSE), Controlled Oral Word Association Test. RESULTS: Results indicate that semantic and phonemic fluency were significant predictors of diagnostic classification, and semantic fluency explained a greater amount of the discriminant ability of the model. CONCLUSIONS: These results suggest that verbal fluency, particularly semantic fluency, may be an accurate and efficient tool in screening for early dementia in time-limited medical settings.