Priming of mice lymphocytes for secretion of IFN#gamma# by heat shock protein--MUC1 fusion protein

作者：Dapeng Li, Li Wang, Hongfei Wei, Peiyin Zhang, Xiuli Wu, Min Wan, Yanmei Wang, Aili Wang, Shijie Yang, Liying Wang · 发表于：Journal of Jilin University · 年份：2004 · 研究领域：Immune Response and Inflammation、Heat shock proteins research、Monoclonal and Polyclonal Antibodies Research

The lymphocytes from the mice immunized by HSP65-MUC1 fusion protein produced much more IFN#gamma# compared with those from control mice in the presence of specific or nonspecific stimulators. HSP65-MUC1 fusion protein plays in important role in the priming of mice lymphocytes for the secretion of IFN#gamma#.