Current Trends in the Development of Nitric Oxide Donors

作者：Yupeng Hou, Adam Jañczuk, P. G. Wang · 发表于：Current Pharmaceutical Design · 年份：1999 · DOI：10.2174/138161280506230110111042 · 被引用次数：229 · 研究领域：Anesthesia and Neurotoxicity Research、Nitric Oxide and Endothelin Effects

Nitric oxide (NO) is an important messenger molecule involved in many pathological and physiological processes within the mammalian body. Exogenous NO sources constitute a powerful way to supplement NO when the body can not generate enough for normal biological functions. In this article, general aspects on NO and NO donors are reviewed. Major focus is placed on recent developments of novel NO donors, NO releasing device(s) as well as innovative improvements to current NO donors. Finally, an outlook on future NO donor development is provided.