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Synthesis and antimicrobial evaluation of novel lipophilic derivatives of pyrazolylisoxazolines

作者:Shally Chadha, Rajni Khajuria, Satya Paul, Kamal K. Kapoor · 年份:2013 · 被引用次数:2 · 研究领域:Synthesis and biological activity、Synthesis of heterocyclic compounds、Multicomponent Synthesis of Heterocycles

A series of novel 3�-(3-phenyl-3,4-dihydro-2H-pyrazol-5-yl)-2,2-dimethylspiro{bicyclo[2.2.1]heptan-3,5�-isoxazoline2�}, 3�-(2,3-diphenyl-3,4-dihydropyrazol-5-yl)-2,2-dimethylspiro{bicyclo[2.2.1]heptan-3,5�-isoxazoline-2�} and 5-octyl-3(3-phenyl-3,4-dihydro-2H-pyrazol-5-yl)isoxazoline-2, 5-decyl-3-(2,3-diphenyl--3,4-dihydropyrazol-5-yl)isoxazoline-2 have been prepared and screened for their antibacterial and antifungal activities.