A Rapid Method for Blood Alcohol Determination by Headspace Analysis Using an Electrochemical Detector

作者：Alan Wayne Jones · 发表于：Journal of Forensic Sciences · 年份：1978 · DOI：10.1520/jfs10759j · 被引用次数：26 · 研究领域：Forensic Toxicology and Drug Analysis、Alcohol Consumption and Health Effects、Advanced Chemical Sensor Technologies

A method for the determination of blood alcohol concentration by headspace analysis using an electrochemical detector is described. A determination can be made within 2 min, and only 0.1 ml of blood is required for each analysis. The detector response was linearly related to ethanol concentrations up to 3.0 mg/ml. The standard deviation of a single determination was +/- 0.014 mg/ml. The accuracy of the method based on comparison with an enzymatic (alcohol dehydrogenase) technique was high, the mean recovery being 102.2% of the attributed concentration. The ease of the operation and fast analysis time make the method ideal for serial determinations, for example during mass screening of biological samples for ethyl alcohol in forensic and toxicology laboratories.