Gut Microbiota and Colonization Resistance against Bacterial Enteric Infection

作者：Quinten R. Ducarmon, Romy Daniëlle Zwittink, Bastian Volker Helmut Hornung, Willem van Schaik, Vincent Bensan Young, Ed J. Kuijper · 发表于：Microbiology and Molecular Biology Reviews · 年份：2019 · DOI：10.1128/mmbr.00007-19 · 被引用次数：568 · 研究领域：Gut microbiota and health、Clostridium difficile and Clostridium perfringens research、Probiotics and Fermented Foods

The gut microbiome is critical in providing resistance against colonization by exogenous microorganisms. The mechanisms via which the gut microbiota provide colonization resistance (CR) have not been fully elucidated, but they include secretion of antimicrobial products, nutrient competition, support of gut barrier integrity, and bacteriophage deployment.