Prevalence of comorbid major depressive disorder in Type 2 diabetes: a meta‐analysis of comparative and epidemiological studies

作者：F. Wang, Siyuan Wang, Qian Zong, QinXiu Zhang, C.H. Ng, Gabor Sandor Ungvari, Yu‐Tao Xiang · 发表于：Diabetic Medicine · 年份：2019 · DOI：10.1111/dme.14042 · 被引用次数：110 · 研究领域：Diabetes Management and Education、Cardiac Health and Mental Health、Chronic Disease Management Strategies

AIMS: To examine the average point prevalence of major depressive disorder in people with Type 2 diabetes and its associated factors in a comprehensive meta-analysis. METHODS: Two researchers independently conducted a systematic literature search of PubMed, EMBASE, PsycINFO and Cochrane databases. Studies reporting the prevalence of major depressive disorder in people with Type 2 diabetes were identified and analysed using a random-effects model. RESULTS: A total of 26 studies meeting the inclusion criteria were included in the study. The point prevalence of major depressive disorder was 14.5% (95% CI 7.9-25.3; I²=99.65). People with Type 2 diabetes were more likely to have major depressive disorder compared with the general population (odds ratio 1.73, 95% CI 1.38-2.16). Subgroup and meta-regression analyses showed that study site, study type, diagnostic criteria and age significantly moderated the prevalence of major depressive disorder. CONCLUSIONS: In this meta-analysis, the average point prevalence of major depressive disorder in people with Type 2 diabetes was high. Routine screening and more effective interventions should be implemented for this population.