Chimeric Antigen Receptor T-Cell Therapy: What the Neuroradiologist Needs to Know

作者：Hardik Valand, Fahimul Huda, Ruiqin Tu · 发表于：American Journal of Neuroradiology · 年份：2019 · DOI：10.3174/ajnr.a6042 · 被引用次数：17 · 研究领域：CAR-T cell therapy research、Nanowire Synthesis and Applications、Integrated Circuits and Semiconductor Failure Analysis

Chimeric antigen receptor T-cell therapy is an exciting and rapidly emerging "fifth pillar" treatment for hematologic cancers. Unique treatment-related toxicities and cost remain a major hindrance to its widespread application. The commonly faced challenges with this innovative therapy, its neurotoxicity, and manifestation on neuroimaging studies, are reviewed.