PD07-07 GERMLINE MUTATION TESTING IN PATIENTS WITH RENAL CELL CARCINOMA IN ENRICHED PATIENT POPULATIONS

作者：Mark Ball, Christopher J. Ricketts, Cathy D. Vocke, Laura S. Schmidt, Martin Lang, C.D.M. Drew, Deborah Nielsen, Lindsay Middleton, Marston Linehan · 发表于：The Journal of Urology · 年份：2019 · DOI：10.1097/01.ju.0000555240.19875.55 · 研究领域：Renal cell carcinoma treatment、Renal and related cancers、Cancer Genomics and Diagnostics

You have accessJournal of UrologyKidney Cancer: Epidemiology & Evaluation/Staging/Surveillance I (PD07)1 Apr 2019PD07-07 GERMLINE MUTATION TESTING IN PATIENTS WITH RENAL CELL CARCINOMA IN ENRICHED PATIENT POPULATIONS Mark Ball*, Christopher Ricketts, Cathy Vocke, Laura Schmidt, Martin Lang, Caitlin Drew, Deborah Nielsen, Lindsay Middleton, and Marston Linehan Mark Ball*Mark Ball* More articles by this author , Christopher RickettsChristopher Ricketts More articles by this author , Cathy VockeCathy Vocke More articles by this author , Laura SchmidtLaura Schmidt More articles by this author , Martin LangMartin Lang More articles by this author , Caitlin DrewCaitlin Drew More articles by this author , Deborah NielsenDeborah Nielsen More articles by this author , Lindsay MiddletonLindsay Middleton More articles by this author , and Marston LinehanMarston Linehan More articles by this author View All Author Informationhttps://doi.org/10.1097/01.JU.0000555240.19875.55AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVES: Renal cell carcinoma (RCC) caused by a known germline genetic alteration accounts for 5-8% of all RCC cases. Some patient populations may be enriched for more frequent germline alterations, including patients with early onset (EO) (age of diagnosis < 46) RCC, bilateral multifocal (BMF) RCC, or familial renal cancer (FRC). We sought to characterize the frequency of p...